Could you please review some strategies for improving the ethical practices of animal testing?© BrainMass Inc. brainmass.com September 27, 2022, 11:12 am ad1c9bdddf
SOLUTION This solution is FREE courtesy of BrainMass!
Animal testing is commonly employed in toxicological studies. In order to reduce unnecessary suffering to animals, methods and alternatives for harm reduction are vital.
A recommended solution is to use the 3Rs method: Replace, Reduce and Refine
Replace: To substitute the use of animals in toxicological testing with alternatives ie. cell cultures or assays, in-silico testing (computer modelling and simulation)
Reduce: To reduce the number of animals needed in a test, ie. by performing multiple dose testings on one animal, or reuse animals for different tests where possible.
Refine: To alleviate harm or pain to animals ie. by administering analgesics before painful procedures, or providing good living conditions for animals
Evaluation of action plan can be carried out at planned intervals to look at:
a. reduction numbers in animals used for testing over time
b. harm reduction on animals, ie. measuring stress level of animals over time using suitable surrogate measures
Further detailed information can be obtained from references below:
1. A report on methods to reduce, refine and replace animal testing in industrial toxicology laboratories. (Accessed: http://www.ncbi.nlm.nih.gov/pubmed/2598088)
2. Alternatives & the 3Rs (Accessed: http://www.animalresearch.info/en/science/alternatives)
3. Since You Asked - Alternatives to Animal Testing (Accessed: http://www.niehs.nih.gov/news/sya/sya-iccvam/#a11443)
4.NC3Rs - National Centre for Replacement, Refinement and Reduction of Animals in Research (Accessed: http://www.nc3rs.org.uk/ )