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Hypothesis Testing of Proportions

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awson and Jick [1976] compare drug prescription in the United States and Scotland.
(a) In patients with congestive heart failure, two or more drugs were prescribed in 257 of 437 U.S. patients. In Scotland, 39 of 179 patients had two or more drugs prescribed. Test the null hypothesis of equal proportions giving the resulting p- value. Construct a 95% confidence interval for the difference in proportions.

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Hypothesis testing of proportions are examined.

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Biostatistics
Awson and Jick [1976] compare drug prescription in the United States and Scotland.
(a) In patients with congestive heart failure, two or more drugs were prescribed in 257 of 437 U.S. patients. In Scotland, 39 of 179 patients had two or more drugs prescribed. Test the null hypothesis of equal proportions giving the resulting p- value. Construct a 95% confidence interval for the difference in proportions.
Answer
The null hypothesis tested is
H0: There is no significant difference in the proportion of patients had two or more drugs prescribed in the United States and Scotland (P1 = P2)
The alternative hypothesis is
H1: There is ...

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