Online TA Profiles
Monica Tory, MSc
OTA ID#: 102792
| Education Experience: |
BSc (Honours), Biochemistry, University of Waterloo, 1994 MSc, Biochemistry, University of Guelph , 1997 |
|---|---|
| Focus of Study: | Biochemistry/Applied Biochemistry and Biophysics
Thesis: Colicin E1 channel peptide-membrane interactions: A biophysical approach to the molecular state, binding, and solvent dynamics. |
| Awards: | Imperial Oil Higher Education Scholarship |
| Publications: | Referenced Publications
Tory & Merrill, 2002. Determination of membrane protein topology by red-edge excitation shift analysis: Application to the membrane-bound colicin E1 channel peptide. Biochim. Biophys. Acta. 1564, 435-448. Yan et al., 1999. Membrane-anchored aspartyl protease with beta-secretase activity of Alzheimers disease. Nature. 402, 533-537. Tory & Merrill, 1999. Adventures in Membrane Protein Topology: A Study of the Membrane-Bound State of Colicin E1. J. Biol. Chem. 274, 24539-49. |
| Work Experience: | Research Biochemist, Pharmacia Corporation
1999-present Applied Biochemistry and Biophysics Research for Drug Discovery and Development Research Technician, University of Guelph (ON, Canada) 1997-1999 Applied biochemistry & biophysics research on protein-membrane interactions, enzymes. Teaching Assistant, University of Guelph (ON, Canada) 1996-1999 Instructed & Evaluated laboratory courses, reports, and exams in introductory chemistry and biochemistry, analytical biochemistry, and enzymology |
| Skills & Achievements: | 4 years industry research experience & 2 years academic research experience in applied biochemistry (protein science, enzymology, assay design/validation/development). |
| Career Interests: | At present, I am enjoying pursuing premier level research in applied biochemistry, for drug discovery and development in the infectious disease and CNS disorder areas.
In the future, I am interested in using my research experience as a foundation for instructing Biochemistry at the College & University levels. |
| Outside Interests: | Competitive swimming, Triathlon, Cooking, and Travel. |
| Message to Students and/or Parents: |
I look forward to helping you improve your understanding of biochemistry!
I offer 4 years experience instructing introductory and advanced Biochemistry laboratories, as well as introductory level chemistry laboratories. During that time period, I also provided one-on-one tutoring to undergraduate students. I invite students of biochemistry/biology/chemistry at the high school or University level to contact me. I am interested in helping with all aspects of biochemistry problems, and would also consider assisting with proof-reading laboratory reports. I especially enjoy assisting students to understand the (somewhat daunting!) concepts of buffer calculations and metabolic cycles. |
| Postings Answered: | 104 |
| Cumulative OTA Rating: | 3.8/5 What is OTA Rating? |
- Solutions : Molarity; understanding acid-base titrations and balanced equations, C1V1=C2V2 - I am confused on how to calculate the concentratin of the HCl solution - below are the answers so far that I have to get the final answer -please help. I am stumped on question 2 The concentration o ...
- Understanding and using the Henri-Michaelis-Menten equation. - For an enzyme which obeys Henri-Michaelis-Menten kinetics, (1) At what substrate concentration will an enzyme characterized by a kcat of 30 s-1 and Km of 0.005 M show one quarter of its maximal rate ...
- The calculation of the isoelectric point (pI) of an amino acid. General method, step by step solutions to the problems, and definitions of concepts/terms provided. - Calculate the isoelectric point (pI) of each of the following amino acids (a) glycine (b) glutamic acid (c) arginine
- Understanding the differences between cell-mediated and antibody-mediated immunity. - What is the difference between cell-mediated immunity and antibody-mediated immunity?
- Understanding nucleic acids, DNA, RNA, transcription - Given the DNA sequence shown below, what is the complementary sequence in (a) DNA and (b) mRNA? 5'AAGGTCAGCTAGGGACTTTTCCCAGGTC-3'
- Enzyme Kinetics: Understanding the Henri-Michaelis-Menten equation/model. - An enzyme with a Km of 0.36 mM was assayed using substrate concentrations of 3 x 10E-7 M, 9.5 x 10E-5 M, 1.5 x 10E-4, 1.16x10E-3, 3 x 10E-3 M, 0.01 M, 0.08 M. At a substrate concentration of 0.08 M, ...
- Understanding under what conditions an enzyme achieves maximal velocity (Vmax) and the turnover number of an enzyme. - The enzyme carbonic anhydrase is found in erythrocytes, and has a molecular mass of approximately 30000 Da. The hydration reaction catalyzed by this enzyme is reversible, and plays a role in the tran ...
- Understanding the characteristics of the different immune responses. - Define five characteristic features of immune responses.
- Understanding the differences between 'natural immunity' and 'specific acquired immunity' - Compare "natural immunity" to "specific acquired immunity".
- Determining the factors in freezing temperatures. - Are the freezing temperatures of 1.00M solutions of NaCl in water and FeCl3 in water the same or different? Why or why not?
- Understanding antigens and antibodies in relation to the immune system. - Explain the relationship of an antigen and antibody.
- Relationships between wavelength, frequency, and energy of light - Calculate the frequency, in units of "per second", of light with a wavelength of (a) 540 nm, and (b) 650 nm.
- Understanding how the equilibrium constant (Keq) relates to enthalpy change. Introductory thermodynamics. Attachment in Word. - Which reaction is more exothermic? A reaction with Keq=500 or a reaction with Keq=0.002?
- Understanding Mendelian genetic heredity. - Consider the cross Aa Bb Cc Dd Ee x aa Bb cc Dd ee (a) What proportion of progeny will PHENOTYPICALLY resemble (1) the first parent (2) the second parent (3) either parent (4) neither pare ...
- Defining homeostasis - Homeostasis means (a) maintenance of a stable internal environment (b) integrating the functions of the various organ systems (c) preventing any change in the organism
- Understanding the immune response. - Explain the role of major histocompatibility (MHC) molecules.
- Understanding the ideal gas law. Using the ideal gas law to calculate work done as a result of a chemical reaction that generates a gas. - Calculate the work done when 50 g of iron dissolves in hydrochloric acid in (a) a closed vessel and (b) an open beaker. Hint: Use the ideal gas law and equations to determine amount of work done w ...
- Understanding how a real gas (eg. van der Waals gas) differs from an ideal gas. Interpreting the pressure-volume behaviour of gases. - In an industrial process, nitrogen has to be heated to 500K at constant volume. If it enters the system at 300 K and 100 atm, what pressure does it exert at its final working temperature? Treat it ...
- Understanding the structure and stability of base pairing in DNA. Predicting relative melting temperature (Tm) for DNA fragments. - Two duplex (ie. double stranded) DNA fragments are shown below. Under identical conditions (ie. ionic strength, buffer composition, temperature, etc.), which double-stranded fragment would denature a ...
- Determining what monomer when undergoing addition polymerization will produce the given polymer. - What monomer when addition polymerized will produce the following polymer? Please see the attachment below.
