Purchase Solution

Enzymatic rate laws

Not what you're looking for?

Ask Custom Question

We are given:
k1 [ES]= [E][S] / Km
E+S---->ES
<---- with Km=(k1+K3)/K1
k1'

k2 material balance gives:
E+I------>EI
<------ [Eo] = [E][S]/Km + [E][I]Ki
k2'
where Ki=[EI]/ [E][I] is the equilibrium constant
k3 for step 2 on the left.

ES--------->E+P

Use this to show that the initial reaction rate is given by:

k3[E]o[S]
v=d[P]/dt=----------------------------- approximately=to k3[E]o[S]o/Km+[S]o
Km+[S]+KmKi[I]

Purchase this Solution
Solution Summary

This solution is provided in 335 words. It uses step-by-step problem to simplify the expression.

Solution Preview

The first thing to realize is what we are looking for...

d[P]/dt = k3[ES] "from last reaction"

substitute in for [ES]
d[P]/dt = k3*([E][S]/km) "from first relationship [ES]= [E][S] / Km"

Notice that [E] is not in the intital reaction rate wanted. Thus we need to get rid ...

Purchase this Solution
Free BrainMass Quizzes
General Chemistry - Classification of Matter

This test will assess your knowledge on the classification of matter which includes elements, compounds and mixtures.

Organic Chemistry Naming: Alkanes

This is a quiz which is designed to assist students with learning the nomenclature used to identify organic compounds. This quiz focuses on the organic compounds called Alkanes.

Periodic table

Match Elements with their Symbols

Elements are provided: choose the matching one- or two-letter symbol for each element.

Functional groups in Organic Chemistry

You will be tested on the names of functional groups in Organic Chemistry. It is very important to know the functional groups to understand Organic reactions.

View More Free Quizzes
Related BrainMass Solutions

  • Acidic Fluid and Enzymatic Activity Experiment Example

    562192 Acidic Fluid and Enzymatic Activity Experiment Example Describe an experiment in which you can test the effect of an acidic fluid on enzymatic activity that include one substrate, one enzyme, and one acidic fluid?

  • Enzymatic Reactions

    Eventually the rate of the reaction reaches a maximum, where further increases in the concentration of the substrate has no affect on the reaction rate. This kind of event is common to many enzymatic reactions.

  • Enzymatic Activity that Protects the Cell from Damage

    170350 Enzymatic Activity that Protects the Cell from Damage Describe the enzymatic activities used by cells to protect themselves from oxidative damage.

  • Atmospheric Change

    Therefore most enzymatic reactions in the cells will not be able to occur and most likely the cell will die or will experience a stunted growth. The heat generated from the greenhouse effect will also hamper enzymatic reactions in the cell.

  • digestive process

    The fundus: this is the upper portion of the stomach where food is ground, mixed and held for further enzymatic digestion.

  • Intracellular second messenger

    This decrease is thought to affect the transduction mechanism in a number of ways, predominantly by modulating the rate of cGMP synthesis from GMP. The enzyme here is guanylyl cylase.

  • Enzymatically Recombinant cIII Deacytylases

    Enzymatic activity of sirtuin can be measured in vitro using recombinant proteins purified from mammalian cells after overexpression or after purification from Escherichia coli.

  • How drugs for leukemia are broken down in the body.

    The more likely scenario however, is enzymatic conversion via the liver.

  • Allosteric Enzymes

    By responding to certain signals in the cell, it is able to control the enzymatic activity - that is increase or decrease activity.

View More Related Solutions