Purchase Solution

Aromatic Alkylation

Not what you're looking for?

Ask Custom Question

Given that the PKa of H2SO4 is -9 and that of HNO3 is -1.4, explain why nitration occurs more rapidly in a mixture of concentrated nitric and sulfuric acids than in concentrated nitric acid alone. Make sure you use equations and the mechanism of formation of the nitronium ion(NO2+) to support your answer.

Purchase this Solution
Solution Summary

This solution explains the rate of nitration in nitric and sulfuric acids with reaction mechanism diagrams and chemical equations. All reaction steps are shown with justifications.

Solution Preview

Dear Student,

Please find solved assignment along with mechanism.

Given that the pKa of H2SO4 is -9 and that of HNO3 is -1.4, explain why nitration occurs more rapidly in a mixture of concentrated nitric and sulfuric acids than in concentrated nitric acid ...

Purchase this Solution
Free BrainMass Quizzes
Periodic table

Thermochemistry

The quiz helps in revising basic concepts about thermochemistry.

Functional groups in Organic Chemistry

You will be tested on the names of functional groups in Organic Chemistry. It is very important to know the functional groups to understand Organic reactions.

Organic Chemistry Naming: Alkanes

This is a quiz which is designed to assist students with learning the nomenclature used to identify organic compounds. This quiz focuses on the organic compounds called Alkanes.

General Chemistry - Classification of Matter

This test will assess your knowledge on the classification of matter which includes elements, compounds and mixtures.

View More Free Quizzes
Related BrainMass Solutions

  • SNAr Mechanism of Piperidine with 2,4-Dinitrobenzene & Meisenheimer Complex Synthesis

    So here the nuleophile is the piperidine and it attaches to the aromatic ring at the most positive point on the aromatic structure. The Chlorine substituted carbon is that point.

  • Rate of Electrophilic Substitution

    Why some aromatic additions happens fast and some happens slow Hi, halogenation of benzene happens fast while alkylation happens slow. Why is it so? The question is described in the attachment please go there for the whole question. Thanks!

  • Friedel-Crafts Alkylation and Acylation, Nitration

    When performing a Friedel-Crafts alkylation reaction, not only does one have the problems of multiple alkylation and rearrangement of the cation, but the presence of strong electron donating groups prevents reaction.

  • synthesis of 4-isopropylbenzonitrile

    The correct answer is b.The order should be first Friedel Craft's alkylation,followed by nitration, reduction, diazotization and reaction w/ CuCN. So (b) is the choice.

  • Cesium Salts in Organic Synthesis

    Instead, cesium carboxylate is much better, with O-alkylation in DMF and heat to yield the ester product.

  • Retrosynthetic Analyses Involving Alkylation of an Alkynide Ion

    8994 Retrosynthetic Analyses Involving Alkylation of an Alkynide Ion Questions on Retrosynthetic analyses involving alkylation of an alkynide ion. Please help me with attached problems 2, 3, and 4. Thanks very much!

  • Acid-Catalyzed Conversion and Self-Condensation

    In the alkylation of cyclohexanone, better yields are obtained by first reacting cyclohexanone with an equivalent of lithiumdiisopropylamide in THF and then adding the alkyl halide, rather than mixing cyclohexanone, alkyl halide, and a catalytic amount

  • Aromatic Compounds in Biological Systems

    Thiamine (B1) is aromatic. So is riboflavin, etc. Ubiquinone, one of the main electron transport carriers in the inner mitochondrial membrane is aromatic.

  • Regiochemistry and product ratios of aromatic reactions

    472807 Regiochemistry and Product Ratios of Aromatic Reactions How does one predict the regiochemistry of the products of aromatic reactions like nitration? What factors are responsible for the product ratios seen in such reactions?

View More Related Solutions