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ICP-MS: Elemental analysis, sensitivity and potential uses

Write a brief account on the use of ICP-MS. Describe the Factors influencing the sensitivity of the elements being measured and potential use of ICP-MS besides total elemental analysis.

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Write a brief account on the use of ICP-MS.

ICP-MS (Inductively Coupled Plasma Mass Spectrometry) is a type of mass spectrometry that is highly sensitive and capable of the determination of a range of metals and several non-metals at concentrations below one part in 1012. It is based on coupling together an inductively coupled plasma as a method of producing ions (ionization) with a mass spectrometer as a method of separating and detecting the ions.


Inductively Coupled Plasma Mass Spectrometry (ICP-MS) is a very powerful tool for trace (ppb-ppm) and ultra-trace (ppq-ppb) elemental analysis. ICP-MS is rapidly becoming the technique of choice in many analytical laboratories for the accurate and precise measurements needed for today's demanding applications. IBecause of its superior sensitivity, ICP-MS should be the method of choice for most determinations of trace elements. Many applications have been reported in the medical and safety fields. Pharmaceutical manufacturers have used it to test for trace elements in very expensive drugs as ICP-MS requires little sample to reach the levels of traditional methods. ICP-MS is an important analytical technique for the pharmaceutical, food and beverage and environmental ...

Solution Summary

This solution provides a brief account on ICP-MS. It then discusses the uses of the technique. It then includes the factors thta influence the sensitivity of elements being measured. Finally it discusses the potential use of ICP-MS besides total elemental analysis.