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Chromium and its effects upon Ingestion

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Please help summarize the mechansim of action of sodium dichromate upon human ingestion.

Also what does the interaction of copper sulfate with sodium dichromate do in a water situation? Does it change Cr (VI) to Cr (III)?

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Chromium's effects upon ingestion are explored in the solution.

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Upon ingestion, sodium dichromate enters the gastrointestinal tract, inducing abdominal pain,burning sensation, diarrhea, nausea, shock or collapse and vomiting.Chromium is not biotransformed, but Cr(VI) undergoes enzymatic reduction, resulting in the formation of reactive intermediates and Cr(III) (Hamilton and Wetterhahn, 1988). The main routes for the excretion of chromium are via the kidneys/urine and the bile/feces; minor routes include milk, sweat, hair, and nails (Guthrie, 1982; Langard, 1982). Studies in humans and/or animals have ...

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