Biochemistry multiple choice questions

Question 4 (1 point)

Assume the pKa's of His are as follows. N term 10, C term 4, Side Chain 6. What is the net charge on the amino acid at pH 6.0

a. 1+

b. 1-

c. 1/2 +

d. 1/2 -

Question 5 (1 point)

Somehow you force the side chain of lysine into a micelle. In aqueous solution the side chain has a pKa of 10.53 What would the pKa of the Lys side chain be inside the micelle?

a. greater than 10.53

b. less than 10.53

c. equal to 10.53

d. insufficient information given

Question 6 (1 point)

A histine side chain is buried inside a protein adjacent to deprotonated Asp. The pKa of the buried his is:

a. greater than its normal value in aqueous solution.

b. less than its normal value in aqueous solution

c. equal to its normal value in aqueous solution

d. insufficient information given