Please explain the applications of FISH (fluorescence in situ hybridization) in medicine. Additionally, differentiate between the different types of FISH by indicating when it is appropriate to use each technique.© BrainMass Inc. brainmass.com October 10, 2019, 4:48 am ad1c9bdddf
Fluorescence in situ hybridization (FISH) is a technique used in biomedical research and medicine to locate particular DNA sequences or to detect the gene expression. It works by creating a probe that will bind to the target nucleotide sequence it was made for. The probe is a nucleotide sequence that will bind to a complementary base pair to the target DNA sequence. Attached to this sequence is a fluorescence probe that will allow one to detect the sequence.
This technique has wide applications in biomedical research. For instance:
This solution explains the applications of fluorescence in situ hybridization (FISH) in medicine. Additionally, it lists the different types of FISH and explains what each type is used for (i.e. what it is used to detect) to help the reader differentiate between them.