Bipolar Disorder and Schizophrenia and genetic roots
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The connection among Bipolar Disorder and Schizophrenia with overlapping genetic roots is assessed.
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The article by Gever (2009) provides some evidence (Lichtenstein, et al, 2009, and others) to suggest that Bipolar Disorder and Schizophrenia have overlapping genetic roots and he argues that this supports the idea that these two disorders should therefore no longer be considered distinct disorders.
It is well known that that both disorders run in families. Although "molecular genetic studies, autopsy findings, and the substantial numbers of patients with symptoms of both disorders have prompted suggestions that they share etiologies" (Gever, 2009); Gever points out that several studies have failed to find any genetic overlap or increased risks within families. Therefore, there are mixed reviews. ...
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