Typically each end of a myosin filament has about 100 myosin molecules pulling in the same direction. Under physiological conditions each myosin can exert a force of about 5.3 pN. We get an upper bound on the force the filament can exert by assuming that all of the myosins are simultaneously attached and exerting force. Each ...continues
Ion pump energetics is the focal topic.
Textbooks quote the value of standard free energy change for the hydrolysis of ATP equal to -7.3 kcal/mole. A certain molecular machine uses one ATP per ste and does useful work equal to 14 kT. This job reconciles these statements, using the fact that typical intracellular concentration are [ATP] = 0.01, [ADP] = .001, and [Pi ...continues
Why can a bumble bee only fly so high ?
Why can a bumble bee only fly so high ?