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Genotypes & Punnett Squares

In fruit flies, the phenotype for eye color is determined by a certain locus. E indicates the dominant allele and e indicates the recessive allele. The cross between a male wild type fruit fly and a female white-eyed fruit fly produced the following offspring.

Wild-type Wild-type White-eyed White-eyed Brown-eyed
male female male female female
F1 0 45 55 0 1

The wild-type and white-eyed individuals from the F1 generation were then crossed to produce the following offspring.

F2 23 31 22 24 0

(a) Determine the genotypes of the original parents (P generation) and explain your reasoning. You may use Punnett squares to enhance your description, but the results from the Punnett squares must be discussed in your answer.
(b) Use a Chi-squared test on the F2 generation data to analyze your prediction of the parental genotypes. Show all your work and explain the importance of your final answer.
(c) The brown-eyed female in the F1 generation resulted from a mutational change. Explain what a mutation is, and discuss two types of mutations that might have produced the brown-eyed female in the F1 generation.

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Elisabeth Nicholson, PhD (IP)

Rating 4.9/5

Active since 2006

BA in Anthropology and Mathematics, Barnard College, Columbia University
PhD in Evolutionary Biology, Northwestern University

Responses 944 | eBooks 2


Comments on Elisabeth's work:

"Should Bold Italic each heading??"

"In your opinion, how long should the summary be?"

"Ok, here goes the re-write as per your suggestion: OLD:This is important to know and will require further research because the same occurrences in the Carver study does have a correlation between those who must have an HR degree in contrast who those with non-HR degree versus those with a professional certification in HR. The new re-write ::This is important to know and will require further research because the same occurrences in the Carver study does have a correlation between those who must have an HR degree to practice than for those with a non-HR degree who can still make a impact.:: You thoughts??"

"Hi Elisabeth, Thank you so much for your help! I was looking for help though with the manual calculations of the part below though so I would know how to do this problem, and cannot turn in my assignment with an online calculator used for the part below. Could you possibly answer the question below without the online calculator? We have to show our work. Thank you! A calculator to automatically solve these probabilities is here: http://www.vassarstats.net/textbook/ch5apx.html Fill in the table on that website with N = 4 and p = 0.5. Change the value of k to e 0, 1, 2, 3, and 4 to find the theoretical probabilities for each possible number of heads. They are: a. Zero Heads = 0.0625 = 6.25% b. One Head = 0.25 = 25% c. Two Heads = 0.375 = 37.5% d. Three Heads = 0.25 = 25% e. Four Heads = 0.0625 = 6.25%"

"Hi Nicole, I have chapter 2 (roughly about 20 pages) for editing, i.e., punctuation etc for your review. Are you still editing? Please advise."


Extracted Content from Question Files:

  • help.doc

In fruit flies, the phenotype for eye color is determined by a certain locus. E indicates the
dominant allele and e indicates the recessive allele. The cross between a male wild type fruit fly
and a female white-eyed fruit fly produced the following offspring.

Wild-type Wild-type White-eyed White-eyed Brown-eyed
male female male female female
F1 0 45 55 0 1

The wild-type and white-eyed individuals from the F1 generation were then crossed to produce
the following offspring.

F2 23 31 22 24 0

(a) Determine the genotypes of the original parents (P generation) and explain your reasoning.
You may use Punnett squares to enhance your description, but the results from the Punnett
squares must be discussed in your answer.
(b) Use a Chi-squared test on the F2 generation data to analyze your prediction of the parental
genotypes. Show all your work and explain the importance of your final answer.
(c) The brown-eyed female in the F1 generation resulted from a mutational change. Explain
what a mutation is, and discuss two types of mutations that might have produced the brown-eyed
female in the F1 generation.